Novel cell-based and materials science approach to target Glioblastoma brain cancer tumors

submitted by: nsf

Stefan Bossmann and Deryl Troyer at Kansas State University are developing a novel materials treatment method for persons with brain cancer that uses a type of white blood cell to deliver anticancer drugs to particularly virulent brain tumors.

New solution for therapeutic cancer vaccine failure

submitted by: mdanderson
http://www.mdanderson.org/newsroom/news-releases/2013/cancer-vaccines-ch... Vaccines designed to turn the immune system against cancer have been logically constructed and tested against many cancers. Almost all have failed or shown minimal effect. They spark creation of killer T cells against the cancer, but generally have little effect on tumors, both in patients and mouse models. Willem Overwijk, Ph.D., and colleagues at MD Anderson discovered that a common vaccine component is...

Research aims to capture, interrogate single cancer cells

submitted by: mdanderson
http://www.mdanderson.org/newsroom/news-releases/2012/project-to-capture... Nicholas Navin, Ph.D., of MD Anderson's Genetics Department, has a plan to sort out the genetic differences among individual tumor cells at different stages of cancer development, then analyze and compare their active mutations. The results should track the evolution of triple-negative breast cancer from initial tumor, to circulating tumor cell to metastatic cell. This new approach, funded by the Damon Runyon...

Bone Cancer Surgery Options for the Adult Patient

submitted by: mdanderson
Valerae Lewis, M.D., Associate Professor in The University of Texas MD Anderson Cancer Center Department of Orthopaedic Oncology, discusses the many surgery options for bone cancer patients. Limb salvage surgery replaces the cancerous bone with either a bone graft from another person (allowgraft), a metal implant or a combination of the two (allo-prosthetic). After amputation of the lower leg, rotationplasty moves the ankle joint to where the knee once was to function as the knee joint. MD...

Brain Cancer Basics and Hope through Research

submitted by: mdanderson
Amy Heimberger, M.D., Associate Professor in the Department Neurosurgery at The University of Texas MD Anderson Cancer Center, discusses the basics, history and the incidence of brain cancer. She is joined by Gail Goodwin, MD Anderson employee and brain cancer survivor, and Lanie Rose, founder of Run for the Rose (annual run raising funds for brain cancer research) for an engaging discussion about new advances in brain cancer research and how there is hope for more long-term brain cancer...

Proton Therapy Treatment for Brain Tumors

submitted by: mdanderson
Download podcast: http://itunes.apple.com/us/itunes-u/what-brain-tumors-are-best/id4318482... ... Proton therapy treatment for brain tumors is the best option for certain cases of brain tumors. Proton therapy causes fewer side effects than traditional radiation and major long term complications are avoided. Radiation is delivered as a proton beam directly to the brain tumor site, sparing healthy tissue. Proton therapy treatment should especially be considered if the affected area includes...

Bone Cancer Surgery Options for the Young Patient

submitted by: mdanderson
Download from iTunes: http://itunes.apple.com/us/itunes-u/bone-cancer-surgery-options/id431848... Osteosarcoma and Ewing's sarcoma are the most common bone tumors found in children. In the past, amputation was the preferred method for removing tumors, but now there are less invasive bone cancer surgery options available. Valerae Lewis, M.D., Associate Professor in the University of Texas MD Anderson Cancer Center Department of Orthopaedic Oncology, discusses limb salvage surgery using an...

Microtubules Keep Tumor Cells Breathing Easy

submitted by: JCB
The transcription factor HIF-1α is essential for a cell's response to low oxygen conditions. Carbonaro et al. demonstrate that production of HIF-1α protein is regulated by dynamic microtubules and that microtubule-targeting drugs shift HIF-1α mRNA into cytoplasmic P-bodies, where its translation is repressed by miRNAs. This biosights episode presents the paper by Carbonaro et al. from the January 10, 2011, issue of The Journal of Cell Biology, and includes an interview with authors Marisa...

The Living Matrix

submitted by: thelivingmatrix
"The Living Matrix: The Science of Healing," trailer; The movie uncovers new ideas about the intricate web of factors that determine our health and interviews a group of dedicated scientists, psychologists, bioenergetic researchers and holistic practitioners, who are finding healing potential in new places. (The energetic information-based medicine looks particularly powerful.) http://www.thelivingmatrixmovie.com/

Array CGH Computational Lab - Chris Miller

submitted by: ralanharris

An introduction to computational methods for analyzing Array Comparative Genomic Hybridization data by Chris Miller. This was presented as a lab within the Computer Aided Discovery Methods course offered within the Graduate Program at Baylor College of Medicine.