Around the Nucleus

submitted by: ahernk

This video is a surreal presentation of a Metabolic Melody by Kevin Ahern ( for more info). The tune is The Beatle's "Across the Universe." The lyrics and video are by Kevin Ahern and the recording is by David Simmons

An Evidence Integration Triangle for Aligning Science with Policy and Practice

submitted by: purcellp
Over-reliance on decontextualized, standardized implementation of eff?cacy evidence has contributed to slow integration of evidence-based interventions into health policy and practice. This article describes an “evidence integration triangle” (EIT) to guide translation, implementation, prevention efforts, comparative effectiveness research, funding, and policy-making. The EIT emphasizes interactions among three related components needed for effective evidence implementation: (1)...
Authors: Russell Glasgow, Lawrence Green, Martina Taylor, Kurt Stange

Microtubules Keep Tumor Cells Breathing Easy

submitted by: JCB
The transcription factor HIF-1α is essential for a cell's response to low oxygen conditions. Carbonaro et al. demonstrate that production of HIF-1α protein is regulated by dynamic microtubules and that microtubule-targeting drugs shift HIF-1α mRNA into cytoplasmic P-bodies, where its translation is repressed by miRNAs. This biosights episode presents the paper by Carbonaro et al. from the January 10, 2011, issue of The Journal of Cell Biology, and includes an interview with authors Marisa...

A Brief Introduction to Genetics

submitted by: dmetzky
A Brief Introduction to Genetics is a short documentary film created using motion graphics as the main visual component. It is a film that explores the history of genetics & genomics and the underlying concepts that provide the foundational knowledge that today's research is built upon. The film describes the history of genetics, from Gregor Mendel, to concepts such as DNA and the genetic code. Having introduced the fundamental ideas of genetics, the film moves on to describe the current...

Progress and Promise in Parkinson's

submitted by: CIRMTV

Parkinson's disease is a neurodegenerative disease that affects nearly a million people in the U.S. No cure exists and current medications become less effective over time. This video provides a patient's perspective of living with Parkinson's and a scientist's efforts to better understand the disease using novel stem cell research strategies.

Progress and Promise in Huntington's

submitted by: CIRMTV

Huntington's disease (HD) is a genetic neurodegenerative disorder that typically strikes in a person's thirties and leads to death 10-15 years later. Through firsthand stories, this video describes the devastating impact of the disease on families, the inspirational power of patient advocacy, and the promise of stem cell research to find a cure.