The Toxic Effects of Cigarette Additives. Philip Morris' Project Mix Reconsidered: An Analysis of Documents Released through Lit

submitted by: glantz
This video describes the peer reviewed paper, Wertz MS, Kyriss T, Paranjape S, Glantz SA (2011) The Toxic Effects of Cigarette Additives. Philip Morris' Project Mix Reconsidered: An Analysis of Documents Released through Litigation. PLoS Med 8(12): e1001145. doi:10.1371/journal.pmed.1001145 Background In 2009, the promulgation of US Food and Drug Administration (FDA) tobacco regulation focused attention on cigarette flavor additives. The tobacco industry had prepared for this...

Evaluation of toxicity and mutagenicity of trichosetin, an anti-MRSA antibiotic

submitted by: UP Los Baños
A report on the UPLB Basic Research Program-funded study aimed to evaluate the potential risk of trichosetin as a therapeutic agent for methicillin- resistant Staphylococcus aureus (MRSA) infection. Speficifically the study determined the (1) oral LD50 of trichosetin in mice, (2) the effect of trichosetin on vital organs, and the (3) mutagenicity of trichosetin. Dr. Eufrocinio C. Marfori National Institute of Molecular Biology and Biotechnology University of the Philippines Los Baños...

Neuropathic Pain Neurodegenerative Disease

submitted by: alex01

Dr. Remi Quirion (McGill University, Montreal, Quebec, Canada) described enhancement of the effects of pain-related peptides by PGE2 . This finding suggests a new, possible complimentary approach to the therapy of pain. Qurion also discussed anti-Alzheimer effect of polyphenols. This effect appears to be due not due to their antioxidant activity only. Quirion suggested the existence of membrane protein than binds polyphenols.