The Importance of Technology in the 'Omics Lab

submitted by: Chrom Solutions

Dr. Matthias Mann, Director of the Max Planck Institute of Biochemistry, talks about how impactful innovative technology, like the Orbitrap, has been in his lab. The end goal of his collaboration with Thermo Fisher Scientific is to build a system that anyone can use to "dramatically extend the reach and impact of proteomics.

Translation Workflow Development using Mass Spectrometry

submitted by: Chrom Solutions
Mary Lopez, Ph.D. discusses translational workflows developed by the BRIMS center, designed to address all aspects of proteomics, from biomarker discovery to developing more routine applications using mass spectrometry. The workflows can be divided into two different types-- discovery and targeted. High-resolution mass spectrometry instruments are used during the discovery phase to analyze complex biological samples in an effort to uncover new biomarkers by looking at differential abundance....

San Jose Facility Now Registered as Medical Device Establishment

submitted by: Chrom Solutions

Thermo Fisher Scientific's San Jose, California facility registered with the U.S. Food and Drug Administration (FDA) as a medical device establishment. The site has established a quality system in accordance with the FDA Quality System Regulations to design and manufacture devices for analyzing samples from patients for in vitro diagnostic use.

Rapid LC-MS Screening and Quantitative Analysis of Pesticides in Food Matrix

submitted by: Chrom Solutions

Charles Yang presents his scientific poster on automated qualitative analysis with enhanced data quality. Using these selective and sensitive methods can provide data for non-targeted, retrospective data analysis without intensive work using a Thermo Scientific Exactive Plus Benchtop Orbitrap Platform.

Plasma-free Metanephrines Quantitation with Automated Online Sample Preparation and a LC/MS Method

submitted by: Chrom Solutions

Xiang (Kevin) He presents his scientific poster about a fast, automated and analytically sensitive LC-MS/MS method developed to quantify plasma metanephrines with significantly simplified sample preparation procedure by using Thermo Scientific TurboFlow™ Technology.

New NanoESI Source for Increased NanoLC-MS Performance in a Plug-and-Spray Configuration

submitted by: Chrom Solutions

Reiko Kiyonami presents her scientific poster about the performance of a new nanospray ion source for increased NanoLC-MS performance with the Thermo Scientific EASY-Spray column, a plug-and-spray configuration. Excellent chromatographic separation with ultra-sharp peaks were achieved, as well as retention-time reproducibility observed over a wide range of flow rates and column temperatures, highlighting the robustness, sensitivity and stability of the system.

Increasing Speed of UHPLC-MS Analysis of Vitamin D for Research Use

submitted by: Chrom Solutions

Sarah Fair presents her scientific poster about removing manual pipetting from the analysis of vitamin D metabolites, testosterone and cortisol using the accuracy and precision of the Thermo Scientific Platemate Pipetting Workstation. Using the automated system offered significant time savings and passed all acceptance criteria for the compounds tested.

Online SPE-LC-APCI-MS/MS for the Determination of Steroidal Hormones in Water

submitted by: Chrom Solutions

Paul Fayad presents his scientific poster about the online SPE-LC-APCI-MS/MS for the determination of steroidal hormones in water using the Thermo Scientific mass spectrometer for a fast and sensitive method allowing the simultaneous determination of 8 selected steroid hormones in water matrices.

Increasing Speed of UHPLC-MS Analysis Using a Thermo Scientific Single-stage Orbitrap Mass Spec

submitted by: Chrom Solutions

Olaf Scheibner presents his scientific poster about increasing the speed of UHPLC-MS methods using a Thermo Scientific Orbitrap mass spectrometer with analysis of complex samples. The results were a significant increase of data quality and improved processing time were achieved due to the reliability and selectivity of the mass spectrometer.

Detection of rHuEPOs in Horse Plasma Samples at Low pgmL Levels using High-Resolution MS Strategies

submitted by: Chrom Solutions

Madalina Oppermann presents her scientific poster about improving the detection and quantification limits for the analysis of recombinant human erythropoietin (rHuEPOs) in horse plasma for doping control using the Thermo Scientific Q Exactive mass spectrometer. The results show the promise of nano-LC-MS/MS analysis on a high-resolution Orbitrap mass analyzer confirm and quatify the rHuEPO target peptides in a single analytical run, with high specificity, sensitivity and resolution.