A diet rich in high glucoraphanin broccoli interacts with genotype to reduce discordance in plasma metabolite profiles through modulating mitochondrial function

submitted by: Andrew Chapple
Background: Observational and experimental studies suggest that diets rich in cruciferous vegetables and glucosinolates may reduce the risk of cancer and cardiovascular disease (CVD). Objective: We tested the hypothesis that a 12-wk dietary intervention with high-glucoraphanin (HG) broccoli would modify biomarkers of CVD risk and plasma metabolite profiles to a greater extent than interventions with standard broccoli or peas. Design: Subjects were randomly assigned to consume 400 g...
Authors: Charlotte Armah, Maria Traka, Jack Dainty, Marianne Defernez, Astrid Janssens, Wing Leung, John Potter, Richard Mithen

Jason Flowers Metabolic Characterization of Candidatus Accumulibacter Phosphatis Using Metaproteomic Analysis

submitted by: dougramsey
In many freshwater bodies, phosphorus is a limiting nutrient for bacterial growth. To prevent eutrophication, enhanced biological phosphorus removal (EBPR) of waste water has been successfully applied at sewage plants for the past thirty years. Previous researchers could only speculate about the biochemical pathways involved in EBPR principally because the organisms responsible for EBPR cannot be isolated in pure culture. Using metagenomic data recently obtained from a Candidatus...