Anesthesia and Incident Dementia

submitted by: WentzMR
Dr. Christopher Jankowski, an Assistant Professor of Anesthesiology from Mayo Clinic in Rochester, MN, shares study results appearing in the June 2013 issue of Mayo Clinic Proceedings. Utilizing data from the Rochester Epidemiology Project, the investigators found no correlation between dementia and exposure to anesthetic agents in older persons undergoing surgical procedures. Available at: http://tinyurl.com/btutmwe

Patients' Perpsective on Full Disclosure Regarding Postoperative Vission Loss

submitted by: mcgheekkm

Dr. Jeffrey Pasternak, Assistant Professor of Anesthesia and Chair of the Neuroanesthesia Division at Mayo Clinic in Rochester, MN, discusses his article appearing in the September 2011 issue of Mayo Clinic Proceedings on informed consent and postopertive vision loss associated with spinal surgery. Available at: http://tinyurl.com/3u7bhql

Tetralogy of Fallot Repair in Patients 40 Years or Older.

submitted by: mcgheekkm

Dr. Joseph Dearani, Consultant in Cardiovascular Surgery at Mayo Clinic, Rochester, MN, discusses his article (available at: http://tinyurl.com/25kt7m6 ) appearing in the December 2010 issue of Mayo Clinic Proceedings, describing surgical repair of tetralogy of fallot in adults.

Factors That Determine Risk for Surgery in Pediatric Patients With Crohn's Disease

submitted by: gastro@scivee

Dr. Neal S. Leleiko discusses his manuscript "Factors That Determine Risk for Surgery in Pediatric Patients With Crohn's Disease". To view the print version of this abstract go to http://tiny.cc/6vrql

A Population-Based Study of Trends in the Use of Total Hip and Total Knee Arthroplasty, 1969-2008

submitted by: mcgheekkm

In this video, Daniel Berry, MD, Professor and Chairman of the Mayo Clinic Department of Orthopedic Surgery discusses the findings of a paper in which he and his coauthors evaluated the utilization rates of total hip and total knee arthroplasty from 1969-2008 in one county in MN.

Heisler et al. Mayo Clinic Proceedings Feb 2010 Article Re: Complication Rates in Patients undergoing Vaginal Hysterectomies

submitted by: mcgheekkm

Dr. Christine Heisler, female pelvic medicine and reconstructive surgeon at Spectrum Health, Grand Rapids, MI, discusses complication rates between local and referral patients undergoing vaginal hysterectomy at Mayo Clinic; this study was published in the February 2010 issue of Mayo Clinic Proceedings.

Treatment of Epilepsy

submitted by: alex01
Michael Rogawski (University of California, Davis) summarizes his research on the antiepileptic activity of neurosteroids (e.g. ganaxolone, allopregnanolone). They are allosteric modulators of GABAA receptors and are active in many models of epilepsy. They are expected, however, to be most effective in catamenial epilepsy, infantile spasms or adult partial seizures. National Institutes of Health (NIH) is currently sponsoring a clinical trial of progesterone (precursor of allopregnanolone)...

TGFß & Alzheimer's Disease

submitted by: alex01

R.A. Flavell (Yale University, New Haven, CT) discusses the role of Transforming Growth Factor ß (TGFß) in disease. In the central nervous system of a murine model of AD this cytokine appears to prevent macrophages from attacking ß-amyloid. Flavell visualizes that selective blockade of this TGFß
activity could lead to the destruction of plaques in patients with AD.