Riboflavin offers a targeted strategy for managing hypertension in patients with the MTHFR 677TT genotype: a 4-y follow-up

submitted by: shaunaharte
ABSTRACT Background: We recently reported that the elevated blood pressure (BP) observed in patients with cardiovascular disease who are homozygous for the 677C/T polymorphism (TT genotype) in the gene encoding methylenetetrahydrofolate reductase (MTHFR) was responsive to supplementation with riboflavin—the cofactor for MTHFR. Objective: The objective was to investigate the effect of riboflavin on BP targeted at patients with the TT genotype 4 y after initial investigation, during...
Authors: Carol P Wilson, Mary Ward, Helene McNulty, J J Strain, Tom G Trouton, Geraldine Horigan, John Purvis, John M Scott

The Commonwealth Shines A Light On The World’s Biggest Killer

submitted by: commonwealthvideo
Learn more on: http://www.thecommonwealth.org Did you know that Non communicable diseases, or NCDs, are the world’s biggest killer? NCDs are diseases like heart disease, stroke, cancer, asthma and diabetes. These diseases are consequences of your lifestyle and the environment you live in. Young people are hit hard by NCDs because lifestyle habits are often adopted at this stage of life and frequently remain well into adulthood. If we act now we can change lives forever. Join the...

Risk factors and determinants for CAD/stroke

submitted by: OxfordJournals

Salim Yusuf in conversation with Thomas Luscher: Risk factors and determinants for CAD/stroke

Joint efforts in the fight against stroke

submitted by: COMED2010

The exploration of neurovascular dysfunction and the perfection of thrombolytic therapy in stroke are two core areas of research pursued by scientists of the European Stroke Network.

Khat Chewing: A Smokeless Gun?

submitted by: mcgheekkm

Dr. Farrah Mateen, a neurology fellow and PhD candidate at Johns Hopkins University discusses her article "Khat Chewing: A Smokeless Gun?" which appears in the November 2010 issue of Mayo Clinic Proceedings. Available at: http://tinyurl.com/24sejsu.

Stroke gene discovered

submitted by: CRoulaux
A Dutch-German medical research team led by Harald Schmidt from Maastricht University, Netherlands, and Christoph Kleinschnitz, University of Würzburg, Germany, in cooperation with Helmholz Zentrum München, has discovered that an enzyme is responsible for the death of nerve cells after a stroke. The enzyme NOX4 produces hydrogen peroxide, a caustic molecule also used in bleaching agents. Inhibition of NOX4 in mice by an experimental new drug dramatically reduces brain damage and preserves...

Endothelial Dysfunction

submitted by: alex01

D. Heistad, MD - Cardiovascular risk factors are associated with endothelial dysfunction. COX-1 inhibition may protect from arterial dysfunction. Potential use of gene therapy in stroke.