Online SPE-LC-APCI-MS/MS for the Determination of Steroidal Hormones in Water

submitted by: Chrom Solutions

Paul Fayad presents his scientific poster about the online SPE-LC-APCI-MS/MS for the determination of steroidal hormones in water using the Thermo Scientific mass spectrometer for a fast and sensitive method allowing the simultaneous determination of 8 selected steroid hormones in water matrices.

Treatment of Epilepsy

submitted by: alex01
Michael Rogawski (University of California, Davis) summarizes his research on the antiepileptic activity of neurosteroids (e.g. ganaxolone, allopregnanolone). They are allosteric modulators of GABAA receptors and are active in many models of epilepsy. They are expected, however, to be most effective in catamenial epilepsy, infantile spasms or adult partial seizures. National Institutes of Health (NIH) is currently sponsoring a clinical trial of progesterone (precursor of allopregnanolone)...