Soy protein diet, but not Lactobacillus rhamnosus GG, decreases mucin-1, trefoil factor-3 and TNFa in colon of dextran sodium sulfate-treated C57BL/6 mice.

submitted by: ruthmacd
The incidence of inflammatory bowel diseases has increased during recent decades. Within the colon, the families of mucins (MUC) and trefoil factors (TFF) facilitate mucosal protection. Probiotic administration influences the intestinal MUC layer. Additionally, food components may affect gut microflora or have direct effects on the MUC barrier. Our objective was to determine whether diet and/or Lactobacillus rhamnosus GG (LGG) would mediate dextran sodium sulfate (DSS)- induced colitis...
Authors: Amy Tentinger, Chad Becker, Byron Brehm-stecher, Joseph Przybyszewski, Debjani Mitra, Huanyi Jiang, Ruth s. Macdonald