SNP

Dr. Adelaide Arruda-Olson, Assistant Professor of Medicine in the Cardiovascular Diseases Research Division at Mayo Clinic in Rochester, MN, discusses her article appearing in the November 2011 issue of Mayo Clinic Proceedings that establishes a relationship between two genetic polymorphisms and the nutrophil count in patients who have experienced a heart attack. Available at: http://www.mayoclinicproceedings.com/content/86/11/1075.abstract.

We use the Ensembl genome browser at www.ensembl.org to view small scale sequence variants such as SNPs (single nucleotide polymorphims) along with larger structural variations like CNVs (copy number variation) for the human ZAP70 gene.

For more information about this resource see our blog post at URL http://blog.openhelix.eu/?p=10091. In today's tip I am going redo a movie originally done by Ensembl on SNP information in Ensembl, but I will use the updated Ensembl release 64.

For more information about this resource, please see our blog post at URL http://blog.openhelix.eu/?p=9933. In this tip I introduce users to the VnD, or genetic Variation and Drug database from the Korean Bioinformation Center, or KOBIC.

Michael Rhodes of Applied Biosystems discusses the SOLiD System at the "Sequencing, Finishing, Analysis in the Future" meeting in Santa Fe, NM on May 27, 2009.

This screencast shows how to identify polymorphic SNPs between different rat strains using RGD's SNPlotyper tool and the STAR consortium SNP genotype dataset. SNPlotyper is available at the Rat Genome Database (http://rgd.mcw.edu) and contains SNP genotype data produced by the european STAR consortium (http://www.snp-star.eu/)