A semaphorin code defines subpopulations of spinal motor neurons during mouse development.

linked profile(s): lydiane
submitted by: apryl
In the spinal cord, motor neurons (MNs) with similar muscle targets and sensory inputs are grouped together into motor pools. To date, relatively little is known about the molecular mechanisms that control the establishment of pool-specific circuitry. Semaphorins, a large family of secreted and cell surface proteins, are important mediators of developmental processes such as axon guidance and cell migration. Here, we used mRNA in situ hybridization to study the expression patterns of...
Authors: Henderson Ce, Mann F., Rougon G, Livet J, Funkelstein L, Cohen S, Castellani V