Cytoskeletal Motor Proteins: Part 3: Mining the Genome for Mitotic Treasures (33:41)

submitted by: scivee-team
The third (last) part of the lecture is on mitosis, the process by which chromosomes are aligned and then segregated during cell division. I will describe our efforts to find new proteins that are important for mitosis through a high throughput RNAi screen. I will discuss how we technically executed the screen and then focus on new proteins that are we discovered that are involved in generating the microtubules that compose the mitotic spindle. I also discuss the medical importance of...

Cytoskeletal Motor Proteins: Part 2: Single Molecule Approaches for Understanding Molecular Motors (25:20)

submitted by: scivee-team

In the second part of this lecture, I will discuss our laboratories current work on the mechanism of movement by dynein, a motor protein about which we still know very little. This is a research story in progress, where some advances have been made. However, much remains to be done in order to understand how this motor works.