The folding and binding landscape of ankyrin repeat proteins

submitted by: icamvid

Elizabeth Komiups gives a talk at the RPP08 conference about the I?B? / NF-?B complex. She discusses the interface between the two proteins, the stabilization of the complex by "hotspots", and the folding of I?B? upon binding.

Directional, Multi- Site Phosphorylations of an SR Protein Splicing Factor

submitted by: icamvid

Joe Adams talks about how splicing kinases phosphorylate multiple serine repeats. The important questions he adresses are whether they are processive or distributive, whether they are regio-specific or residue-specific, and whether they are directional.