HISTORY OF DERMATOLOGY Vitiligo and Leprosy

submitted by: camdic

The vitiligo has long been confused with the leprosy and with other leukoderma diseases, therefore the Hebrew word 'Zora' or 'Tzaraat/Tzoraath' was translated using the Greek word "Lepros" and the Latin word "Lepra". There is a well-known example in the Old Testament. Naaman, captain of the hosts of the King of Syria, (suffering from psoriasis, Russel 1950), on the advice of Elisha, washed seven times in the Jordan to rid himself of 'Zaraath'.

INCONTINENTIA PIGMENTI

submitted by: camdic
Incontinentia pigmenti, is a rare genodermatosis, also called Bloch-Sulzberger syndrome or Bloch-Siemens, that shows early at birth or in the neonatal period. In its classical form, the cutaneous symptomatology develops through three steps. 1st step, with evidence of injuries, of erythematic-vescicular-blistered kind and one wave after another, linearly positioned and involving upper body and limbs;haematic hypereosinophilia is also present. 2nd step, that pops up between the second and...

KINDLER SYNDROME

submitted by: camdic
A case is reported of a 28 year old man referring the appearance of swollen blisters due to insignificant trauma since birth. Later he noticed progressive changes of the skin as teleangectasies, atrophic spots, sensivity to sun, dystrohic fingermails and webbing between fingers. The patient was hospitalized several times for an appropriate diagnosis and asked for the permission to undergo an operation of plastic surgery in Paris to correct webbing of the hands. The rare association of two...

HUTCHINSON-GILFORD SYNDROME

submitted by: camdic

Recent studies suggest that, as in other aging syndromes, the Hutchinson-Gilford syndrome is due at to a defect in the mechanism of DNA repair. Mutations have been found in the Lamin A gene (LMNA) situated on chromosome 1.

LASSUEUR PICCARDI GRAHAM LITTLE Syndrome.

submitted by: camdic

A rare disease in which cicatricial (scarring) alopecia of the scalp is associated with widepsread keratosis pilaris particularly in the axillae and pubic area where scarring does not usually occur. The scarring in the scalp may be clinically indistinguishable from the end stage of other forms of scarring hair loss.(Abstract) Prof. Camillo O. Di Cicco,MD