Translation Workflow Development using Mass Spectrometry

submitted by: Chrom Solutions
Mary Lopez, Ph.D. discusses translational workflows developed by the BRIMS center, designed to address all aspects of proteomics, from biomarker discovery to developing more routine applications using mass spectrometry. The workflows can be divided into two different types-- discovery and targeted. High-resolution mass spectrometry instruments are used during the discovery phase to analyze complex biological samples in an effort to uncover new biomarkers by looking at differential abundance....

Plasma-free Metanephrines Quantitation with Automated Online Sample Preparation and a LC/MS Method

submitted by: Chrom Solutions

Xiang (Kevin) He presents his scientific poster about a fast, automated and analytically sensitive LC-MS/MS method developed to quantify plasma metanephrines with significantly simplified sample preparation procedure by using Thermo Scientific TurboFlow™ Technology.

Increasing Speed of UHPLC-MS Analysis Using a Thermo Scientific Single-stage Orbitrap Mass Spec

submitted by: Chrom Solutions

Olaf Scheibner presents his scientific poster about increasing the speed of UHPLC-MS methods using a Thermo Scientific Orbitrap mass spectrometer with analysis of complex samples. The results were a significant increase of data quality and improved processing time were achieved due to the reliability and selectivity of the mass spectrometer.

Detection of rHuEPOs in Horse Plasma Samples at Low pgmL Levels using High-Resolution MS Strategies

submitted by: Chrom Solutions

Madalina Oppermann presents her scientific poster about improving the detection and quantification limits for the analysis of recombinant human erythropoietin (rHuEPOs) in horse plasma for doping control using the Thermo Scientific Q Exactive mass spectrometer. The results show the promise of nano-LC-MS/MS analysis on a high-resolution Orbitrap mass analyzer confirm and quatify the rHuEPO target peptides in a single analytical run, with high specificity, sensitivity and resolution.