Clinical and microbiological effects of Lactobacillus reuteri probiotics in the treatment of chronic periodontitis: a randomized placebo-controlled study

Aim The aim of this randomized placebo-controlled clinical trial was to evaluate the effects of Lactobacillus reuteri-containing probiotic lozenges as an adjunct to scaling and root planing (SRP). Material and Methods Thirty chronic periodontitis patients were recruited and monitored clinically and microbiologically at baseline, 3, 6, 9 and 12 weeks after therapy. All patients received one-stage full-mouth disinfection and randomly assigned over a test (SRP + probiotic, n = 15) or...
Authors: Wim Teughels, Andac Durukan, Onur Ozcelik, Martine Pauwels, Marc Quirynen, Mehmet Cenk Haytac

The effects of perioperative probiotic treatment on serum zonulin concentration and subsequent postoperative infectious complications after colorectal cancer surgery: a double-center and double-blind randomized clinical trial

submitted by: liuzhh26
Background: Zonulin is a newly discovered protein that has an important role in the regulation of intestinal permeability. Our previous study showed that probiotics can decrease the rate of infectious complications in patients undergoing colectomy for colorectal cancer. Objective: The objective was to determine the effects of the perioperative administration of probiotics on serum zonulin concentrationsand the subsequent effect on postoperative infectious complications in patients...
Authors: Zhi-Hua Liu, Mei-Jin Huang, Xing-Wei Zhang, Lei Wang, Nan-Qi Huang, Hui Peng, Pin Lan, Jun-Sheng Peng, Zhen Yang, Yang Xia, Wei-Jie Liu, Jun Yang, Huan-Long Qin, Jian-Ping Wang

Lactobacillus rhamnosus GG and Bifidobacterium animalis MB5 Induce Intestinal but Not Systemic Antigen-Specific Hyporesponsiveness in Ovalbumin-Immunized Rats

submitted by: mengheri
Probiotics may modulate the host immune response by mechanisms not yet fully understood. We evaluated the modulation of intestinal and systemic antigen-specific immune response by Lactobacillus rhamnosus GG (LGG) or Bifidobacterium animalis MB5 in tolerized and immunized rats. Three groups of rats received orally LGG, B. animalis, or PBS (control) for 28 d. Each group was divided into two subgroups of tolerized or immunized rats receiving orally ovalbumin (OVA; 7 mg) or PBS on d 7, 9, and...
Authors: Alberto Finamore, Marianna Roselli, Maria Serena Britti, Nicolò Merendino, Elena Mengheri

David Relman: The Stability of the Human Microbiome (MWV51)

submitted by: MicrobeWorld
In episode 51 of MicrobeWorld Video, filmed at the American Association for the Advancement of Science Meeting in Washington, D.C., on February 18, 2011, Dr. Stan Maloy talks with David Relamn, M.D., Thomas M. and Joan C. Merigan Professor, Department of Medicine - Division of Infectious Diseases, and Department of Microbiology & Immunology in the Stanford University School of Medicine. Maloy and Relman discuss microbial flora in the mouth and gut and why they are important for human...