Melanin-concentrating hormone receptor 1 polymorphisms are associated with components of energy balance in the CODING study

submitted by: bfontain
BACKGROUND: The melanin-concentrating hormone receptor 1 (MCHR1) is a G protein-coupled receptor that regulates energy balance and body composition in animal models. Inconsistent effects of MCHR1 polymorphisms on energy homeostasis in humans may partly be attributable to environmental factors. OBJECTIVES: We examined the effect of 4 single nucleotide polymorphisms (rs133073, rs133074, rs9611386, and rs882111) in the MCHR1 gene on body composition as well as energy-related lifestyle...
Authors: Bénédicte Fontaine-Bisson, James Thorburn, Anne Gregory, Hongwei Zhang, Guang Sun

Neil Miller on “Genome, epigenome and RNA sequences of monozygotic twins discordant for multiple sclerosis”

submitted by: JGI

Neil Miller, Deputy Director of Software Engineering at the National Center for Genome Resources, discusses a monozygotic twin study on June 2, 2010 at the "Sequencing, Finishing, Analysis in the Future" meeting in Santa Fe, NM.