The Problem of Regeneration: Part 3: Molecular Basis of Regeneration: Planarians as a Model System (43:54)

submitted by: video_collector

In the third and last part of this lecture, I will introduce the model system we have developed to study animal regeneration, the planarian Schmidtea mediterranea. I will review its anatomy, and the biological attributes that make these animals extraordinarily well suited to dissect the molecular and cellular basis of regeneration. I will also discuss recent work from my laboratory aimed at identifying molecules associated with regenerative capacities.

The Problem of Regeneration: Part 2: Principles of Planarian Regeneration (32:49)

submitted by: video_collector

In this second part of the lecture, I will briefly review the rich history of planarian research, followed by a summary of the central principles of planarian regeneration that have been derived from this extensive, often fascinating body of experimental work.

The Problem of Regeneration - Part 1: A Brief (Natural) History of Regeneration (32:38)

submitted by: video_collector
Regeneration has fascinated philosophers and scientists since the beginning of history. The wide but uneven distribution of regenerative capacities among multicellular organisms is puzzling, and the permissive/inhibitory mechanisms regulating this attribute in animals remain a mystery. In the first part of this lecture, I will provide a general history of regeneration research from ancient Greece to the beginning of the 20th century. Key concepts will be introduced in their appropriate...