GenePRIMP: A tool for improving microbial gene prediction quality

submitted by: JGI

Amrita Pati of the DOE Joint Genome Institute's Genome Biology group describes the software tool GenePRIMP and how it fits into the quality control pipeline for microbial genomics. Further details regarding GenePRIMP appear in a paper published online May 2, 2010 in Nature Methods.

Miriam Land on "Automated Microbial Genome Annotation"

submitted by: JGI

Miriam Land of the DOE Joint Genome Institute at Oak Ridge National Laboratory gives a talk on the current state and future challenges of moving toward automated microbial genome annotation at the "Sequencing, Finishing, Analysis in the Future" meeting in Santa Fe, NM on May 29, 2009.

Alla Lapidus on "New technology drafts: production and improvements"

submitted by: JGI

Alla Lapidus, head of the DOE Joint Genome Institute's Finishing group, gives a talk on how the DOE JGI's microbial genome sequencing pipeline has been adapted to accommodate next generation sequencing platforms at the "Sequencing, Finishing, Analysis in the Future" meeting in Santa Fe, NM on May 28, 2009.

Epigenomics of Cancer - Prof. Wei Li (Part 1, 2009)

submitted by: ralanharris

Prof. Wei Li lectures on studies of transcription factor binding sites and histone modifications using ChIP-chip and Chip-seq assays. Part of the Computer Aided Discovery Methods 2009 course offered at Baylor College of Medicine.

Sodium Channels and Pain

submitted by: alex01

S. Waxman, MD, PhD. - Medical need for new analgesics is discussed by S. Waxman (Yale University) who evaluated the role of selective subtypes of sodium channels, particularly 1.7 and 1.8 subtypes, in the perception of pain. There is an unmet medical need for drugs to treat chronic pain and inhibitors of
selective sodium channels are in development as novel analgesics.

Alzheimer's Disease

submitted by: alex01
Z. Khachaturian, PhD. - New approaches to the therapy of Alzheimer’s disease (AD) are discussed in video interviews of this series. According to Z. Khachaturian (Potomac, MD) substantial progress has been made during the last 10 years in our understanding of pathogenesis of Alzheimer’s disease as well as in the discovery of biomarkers and therapeutic approaches. In addition to cholinergic drugs, inhibitors of plaque formation have been discovered, but the currently available...

Talk by Jim Nelson

submitted by: dougramsey

Jim Nelson talks about what needs to be done to help the learning gaps in children of different backgrounds be bridged and points out that one of the causes of the problem is the competency of the teaching staff in terms of education and pedagogic skills.