This is a podcast and slides of a lecture given on Nov 02, 2011 in the course Phar201 (http://www.sdsc.edu/pb/edu/pharm201/) at the University of California San Diego by Prof. Phil Bourne. It covers some aspects of protein ligand interactions with emphasis on SMAP for determining similar ligand binding sites and the pharmacological implications.
This is a podcast and slides of a lecture given on Nov 16, 2011 in the course Phar201 (http://www.sdsc.edu/pb/edu/pharm201/) at the University of California San Diego by Prof. Phil Bourne. It covers determining domains from 3D protein structure.
This is a podcast and slides of a lecture given on Nov 9, 2011 in the course Phar201 (http://www.sdsc.edu/pb/edu/pharm201/) at the University of California San Diego by Prof. Michael Gilson. It covers structure and ligand based structure methods used in drug discovery.
This is a podcast and slides of a lecture given on Nov 4, 2011 in the course Phar201 (http://www.sdsc.edu/pb/edu/pharm201/) at the University of California San Diego by Phil Bourne. It covers one methodology for determining the site of protein-protein interaction when one only has a single structural component of the complex. It is based on the paper found here http://www.sdsc.edu/pb/papers/chung05.pdf
For more information about this resource, please see our blog post at URL http://blog.openhelix.eu/?p=9933. In this tip I introduce users to the VnD, or genetic Variation and Drug database from the Korean Bioinformation Center, or KOBIC.
For more information about these resources see our blog post at URL http://blog.openhelix.eu/?p=9579. In this tip I show you why & how you can move from a UniProt protein report to either an RCSB PDB structure page or to search results in the Structural Biology Knowledgebase that provide information on established protocols and available materials related to the protein of interest.
For more information about this resource please see our blog post at URL http://blog.openhelix.eu/?p=6978. In today's tip I will feature the data distribution summaries and their drill down features which you can see from many RCSB PDB searches.
This week's tip is on PolyPhen, a predictor of nonsynonymous SNP impacts on protein functions. For more information about PolyPhen and SNP functional prediction see the blog post: http://blog.openhelix.eu/?p=6867
This presentation describes my interactions with the San Diego Supercomputer Center (SDSC) over the past 15 years as part of the celebration of 25 years of SDSC which will take place on October 12, 2010.
For more information about this resource see our blog post at URL http://blog.openhelix.eu/?p=4703 on the OpenHelix blog. The PSI Structural Genomics Knowledgebase is a great resource for protein information, including structural information, especially if you are not a structural biologist. In this short movie I will search for a specific Protein Data Bank (PDB) ID & show you the information you can obtain and how it is formatted.
