Deriving rules and assertions from pharmacogenomics knowledge resources in support of patient drug metabolism efficacy...

submitted by: Jamia
Full title: Deriving rules and assertions from pharmacogenomics knowledge resources in support of patient drug metabolism efficacy predictions Abstract: Objective Pharmacogenomics evaluations of variability in drug metabolic processes may be useful for making individual drug response predictions. We present an approach to deriving ‘phenotype scores’ based on existing pharmacogenomics knowledge and a patient's genomics data. Pharmacogenomics plays an important role in the bioactivation...