Potential Adverse Cardiovascular Effects from Excessive Endurance Exercise

submitted by: WentzMR

Dr. James O’Keefe, Clinical Cardiologist from Saint Luke’s Mid America Heart Institute in Kansas City, Missouri, describes the risks and benefits of extreme endurance exercise, emphasizing the importance of moderation. Available at:
http://www.mayoclinicproceedings.org/article/S0025-6196(12)00473-9/fulltext

Rabbit Models for Alzheimer's Disease

submitted by: alex01

Diana Woodruff-Pak (Temple University, Philadelphia, PA) used cholesterol-fed rabbits as a model of AD for evaluation of currently available and potential anti-Alzheimer drugs. These animals developed typical Alzheimer pathology, including behavioral changes and deposition of ß-amyloid and even
tau. Galantamine and donepezil partially protected animals from Alzheimer symptomatology.