open science

Mirza PhD defense on the Ugi reaction for anti-malarial screening

submitted by: jcbradley
Khalid Baig Mirza defends his Ph.D. thesis at Drexel University on December 6, 2010 (advisor JC Bradley). He first discusses Open Notebook Science and his contribution to the sodium hydride oxidation controversy. Then he describes the UsefulChem project, involving the use of the Ugi reaction as an approach to synthesizing new anti-malarial agents, including a few unexpected side reactions and challenges. Finally he presents an overview of the ONS Solubility Challenge and its application to...

Dana Vanderwall on Cheminformatics at Drexel

submitted by: jcbradley
Dana Vanderwall, Associate Director of Cheminformatics at Bristol-Myers Squibb, presented at Drexel University for Jean-Claude Bradley's Chemical Information Retrieval class on December 2, 2010. The first part covers "Cheminformatics & The evolving relationship between data in the public domain & pharma" and includes a general discussion of modern drug discovery and the details of a malaria dataset recently released from the pharmaceutical industry to the public. The second part describes...

Nanoinformatics Talk on SMIRP and Open Notebook Science

submitted by: jcbradley
Jean-Claude Bradley presents on "The implications of Open Notebook Science and other new forms of scientific communication for Nanoinformatics" at the Nanoinformatics 2010 conference on November 3, 2010. The presentation first covers the use of the laboratory knowledge management system SMIRP for nanotechnology applications during the period of 1999-2001 at Drexel University. The exporting of single experiments from SMIRP and publication to the Chemistry Preprint Archive is then described...

Bradley Research at Drexel Chemistry MiniSymposium 2010

submitted by: jcbradley
Jean-Claude Bradley presents a condensed version of ongoing work in his laboratory at Drexel University. Topics covered include Open Notebook Science for malaria drug discovery, the Ugi reaction and the ONS Challenge, a crowdsourcing initiative to collect non-aqueous solubility measurements. Some recent work on using web services to leverage these datasets is also discussed.

A personal perspective on open access publishing

submitted by: phylogenomics
Slidecast of a talk I gave at UC Davis - for the brown bag series for the CTSC (Clinical and Translational Science Center) http://www.ucdmc.ucdavis.edu/ctsc/

OpenSciNY Open Notebook Science Talk

submitted by: jcbradley
On May 14, 2010 Jean-Claude Bradley presented on Open Notebook Science at the OpenSciNY conference at the New York University Library. He introduced the topic by telling a few stories about how new forms of communication are affecting how we think about concepts like "scientific precedent", "peer review", "scientific publishing" and "scientific scholarship". At the end he spoke about archiving Open Notebook Science projects culminating in the publication of the Reaction Attempts and ONS...

Technology and Students: Mix, Match or Miss?

submitted by: jcbradley
Jean-Claude Bradley presents on "Technology and Students - Mix, Match or Miss?" at the Villanova Teaching and Learning Strategies Symposium on May 13, 2010. Topics covered include screencasting, wikis, games and Second Life, with a particular focus on student response to these technologies.

Education 2.0: Leveraging Collaborative Tools for Teaching

submitted by: jcbradley
Jean-Claude Bradley presents at the Drexel E-Learning 2.0 Conference on March 25, 2010. The talk covers the educational uses of screencasting, wikis, blogs, games, Google Spreadsheets and Second Life.

Peer Review and Science2.0

submitted by: jcbradley
Jean-Claude Bradley presents on "Peer Review and Science2.0: blogs, wikis and social networking sites" as a guest lecturer for the “Peer Review Culture in Scholarly Publication and Grantmaking” course at Drexel University. The main thrust of the presentation is that peer review alone is not capable of coping with the increasing flood of scientific information being generated and shared. Arguments are made to show that providing sufficient proof for scientific findings does scale and...

UPenn Library Open Notebook Science Talk Jan2010

submitted by: jcbradley
Jean-Claude Bradley presents "Open Notebook Science and other Science2.0 Approaches to Communicate Research" at the University of Pennsylvania Library on January 21, 2010. The introduction covers recent examples of where the sharing of laboratory notebook information in chemistry on the blogosphere has been key to resolving ambiguous results in the traditional literature. Other examples illustrate the inability to assess contradictory data in the literature simply because insufficient...