History of Medicine. Plague and Vampirism in the Middle Ages.

submitted by: camdic
The Nachzehrer would be a special kind of vampire who lives in a constant state of numbness in his grave, without understanding what is happening around and just like a child, chewing spasmodically his dress. Martin Böhm wrote in 1601: "We have seen in times of the plague how dead people especially women - who have died of the plague make smacking noises in their graves, like a pig that is eating, and that while this smacking is going on the plague becomes much worse, usually in the...

Anesthesia and Incident Dementia

submitted by: WentzMR
Dr. Christopher Jankowski, an Assistant Professor of Anesthesiology from Mayo Clinic in Rochester, MN, shares study results appearing in the June 2013 issue of Mayo Clinic Proceedings. Utilizing data from the Rochester Epidemiology Project, the investigators found no correlation between dementia and exposure to anesthetic agents in older persons undergoing surgical procedures. Available at: http://tinyurl.com/btutmwe

Diagnostic Yield of Electroencephalography in a General Inpatient Population

submitted by: WentzMR

Dr. John Betjemann, an Assistant Clinical Professor of Neurology at the University of California in San Francisco, discusses his article appearing in the April 2013 issue of Mayo Clinic Proceedings, which exposes surprising results of seizure activity in 7% of non-critically ill patients with spells or altered mental status. Available at: http://tinyurl.com/ak9p9d5

Rabbit Models for Alzheimer's Disease

submitted by: alex01

Diana Woodruff-Pak (Temple University, Philadelphia, PA) used cholesterol-fed rabbits as a model of AD for evaluation of currently available and potential anti-Alzheimer drugs. These animals developed typical Alzheimer pathology, including behavioral changes and deposition of ß-amyloid and even
tau. Galantamine and donepezil partially protected animals from Alzheimer symptomatology.

Treatment of Epilepsy

submitted by: alex01
Michael Rogawski (University of California, Davis) summarizes his research on the antiepileptic activity of neurosteroids (e.g. ganaxolone, allopregnanolone). They are allosteric modulators of GABAA receptors and are active in many models of epilepsy. They are expected, however, to be most effective in catamenial epilepsy, infantile spasms or adult partial seizures. National Institutes of Health (NIH) is currently sponsoring a clinical trial of progesterone (precursor of allopregnanolone)...

Alzheimer's Disease

submitted by: alex01
Z. Khachaturian, PhD. - New approaches to the therapy of Alzheimer’s disease (AD) are discussed in video interviews of this series. According to Z. Khachaturian (Potomac, MD) substantial progress has been made during the last 10 years in our understanding of pathogenesis of Alzheimer’s disease as well as in the discovery of biomarkers and therapeutic approaches. In addition to cholinergic drugs, inhibitors of plaque formation have been discovered, but the currently available...

Afasias

submitted by: Alejandro Stern

A demonstration of the effects of Aphasia, the loss of the ability to comprehend and interpret language correctly, due to brain damage or injury.

Accidentes Cerebrovasculares

submitted by: Alejandro Stern

A demonstration of a cerebrovascular accident and how it occurs.Accidentes Cerebrovasculares - ACV