Sodium Channels and Pain

submitted by: alex01

S. Waxman, MD, PhD. - Medical need for new analgesics is discussed by S. Waxman (Yale University) who evaluated the role of selective subtypes of sodium channels, particularly 1.7 and 1.8 subtypes, in the perception of pain. There is an unmet medical need for drugs to treat chronic pain and inhibitors of
selective sodium channels are in development as novel analgesics.

TGFß & Alzheimer's Disease

submitted by: alex01

R.A. Flavell (Yale University, New Haven, CT) discusses the role of Transforming Growth Factor ß (TGFß) in disease. In the central nervous system of a murine model of AD this cytokine appears to prevent macrophages from attacking ß-amyloid. Flavell visualizes that selective blockade of this TGFß
activity could lead to the destruction of plaques in patients with AD.

The Living Matrix

submitted by: thelivingmatrix
"The Living Matrix: The Science of Healing," trailer; The movie uncovers new ideas about the intricate web of factors that determine our health and interviews a group of dedicated scientists, psychologists, bioenergetic researchers and holistic practitioners, who are finding healing potential in new places. (The energetic information-based medicine looks particularly powerful.)

Conus Peptides by Baldomero "Toto" Olivera, May 2006 - Part 1: Historical Background: Discovery of a Drug (23:40)

submitted by: video_collector
Although snails are not the first animals that come to mind when venoms are mentioned, there are in fact a large number (~10,000 species) of different venomous predatory snails. The most intensively studied of these are the cone snails (Conus), which have a large number of peptide neurotoxins present in their venoms. Some cone snail venoms are lethal to man; one species causes a 70% fatality rate. How these venoms have been used to understand the nervous system, and how the characterization...

MacArthur Fellow 2008: Sally Temple, neuroscientist

submitted by: video_collector
Sally Temple is a neuroscientist tracing the natural interactions of differentiating neurons, bringing us closer to developing effective methods for treating central nervous system damage. MacArthur Fellowships offer the opportunity for Fellows to accelerate their current activities or take their work in new directions. The unusual level of independence afforded to Fellows underscores the spirit of freedom intrinsic to creative endeavors. The extraordinary creativity of MacArthur...

Robert Yolken (CNS Disease Session)

submitted by: hhv-6foundation

"Elevated levels of antibodies to HHV-6 in individuals with schizophrenia: Results from a hypothesis generating case-control study among military personnel"
6th International Conference on HHV-6 & 7 in Baltimore, Maryland, USA
Day 3 - June 22, 2008 - CNS Disease Session

Steven Jacobson (CNS Disease Session)

submitted by: hhv-6foundation

"The association of the human herpesvirus-6 (HHV-6) in diseases of the nervous system"
6th International Conference on HHV-6 & 7 in Baltimore, Maryland, USA
Day 3 - June 19-22, 2008 - CNS Disease Session