Metagenomic Comparison of the Microbial Hindgut Communities in Drywood- and Grass-Feeding Termites

submitted by: dougramsey
Falk Warnecke, Microbial Ecology Program, Joint Genome Institute, DOE Co-authors: Natalia Ivanova, Martin Allgaier, Nikos Kyrpides, Rudolf Scheffrahn, and Phil Hugenholtz Termites are highly efficient in degrading lignocellulosic biomass. In a recent metagenomic study we showed for the first time that microbes inhabiting the termite hindgut encode hundreds of carbohydrate-active enzymes, e.g. glycosyl hydrolases (GHs) and tens of carbohydrate binding modules (CBMs) and by implication are...

Efficient Metagenomics Data Processing: Pitfalls and Solutions

submitted by: dougramsey
Nikos Kyrpides, Joint Genome Institute Co-authors: Kostas Mavrommatis, Natalia Ivanova Metagenomics has emerged as a powerful tool for exploration of the functional capabilities of microbial communities regardless of the ability of their members to grow in pure culture. However, little is known for the efficacy of the methods used to process these datasets. Further more, sequencing of environmental genomic DNA usually results in large, highly fragmented datasets representing a significant...