The Spindle's Model Behavior

submitted by: JCB
Dynamic microtubules assemble into a steady state bipolar spindle structure but precisely how this is achieved is unclear. Loughlin et al. develop a computational model that predicts how a few key activities organize microtubules in Xenopus meiotic spindles. This biosights episode presents the paper by Loughlin et al. from the December 27, 2010 issue of The Journal of Cell Biology, and includes an interview with author François Nédélec (EMBL, Heidelberg, Germany). Produced by Caitlin...

Acetylated microtubules let the ER slide

submitted by: JCB
The endoplasmic reticulum is highly dynamic, although little is known about why and how its membrane tubules move. Friedman et al. reveal that ER membranes slide along stable, acetylated microtubules, which might help them contact other organelles such as mitochondria. This biosights episode presents the paper by Friedman et al. from the August 9, 2010 issue of The Journal of Cell Biology, and includes an interview with senior author Gia Voeltz. Produced by Caitlin Sedwick and Ben Short....