Riboflavin offers a targeted strategy for managing hypertension in patients with the MTHFR 677TT genotype: a 4-y follow-up

submitted by: shaunaharte
ABSTRACT Background: We recently reported that the elevated blood pressure (BP) observed in patients with cardiovascular disease who are homozygous for the 677C/T polymorphism (TT genotype) in the gene encoding methylenetetrahydrofolate reductase (MTHFR) was responsive to supplementation with riboflavin—the cofactor for MTHFR. Objective: The objective was to investigate the effect of riboflavin on BP targeted at patients with the TT genotype 4 y after initial investigation, during...
Authors: Carol P Wilson, Mary Ward, Helene McNulty, J J Strain, Tom G Trouton, Geraldine Horigan, John Purvis, John M Scott