Let's Split Mitosis-Style

submitted by: Destroyer501

I, Harold, am playing as a student who got home late and needs to work on a paper for mitosis. As I am working, I realize that I am too tired and need to rest. While I'm leaving I spill my cup and out falls all the materials required in the video onto my paper, displaying some stages of mitosis. While I'm resting, I have a dream of myself rapping about mitosis, explaining some steps and elements of the process.

Moesin keeps mitotic cells in shape

submitted by: JCB
The ERM protein Moesin helps mitotic cells undergo a series of dramatic shape changes by linking the actin cytoskeleton to the plasma membrane. Roubinet et al. describe how Moesin's localization and activity is regulated over the course of the cell cycle by two different pathways that control Moesin phosphorylation and phosphoinositide synthesis. This biosights episode presents the paper by Roubinet et al. from the October 3, 2011, issue of The Journal of Cell Biology, and includes an...

Nuclear envelope starts with a clean sheet

submitted by: JCB
At the start of mitosis, the nuclear envelope and nuclear pore complexes break down and disperse into the endoplasmic reticulum and cytoplasm. Lu et al. use rapid, 3D live cell imaging to reveal that, in contrast to previous models, the nuclear envelope reforms directly from ER cisternae after mitosis and that this happens before nuclear pore complexes start to reassemble. This biosights episode presents the paper by Lu et al. from the August 8, 2011, issue of The Journal of Cell Biology,...

Physics of the Mitotic Spindle, part 2

submitted by: icamvid

Presented at the I2CAM/FAPERJ Spring School, 2008 in Rio de Janeiro, Brazil

Computational Studies of Biological Molecules, part 2; Physics of the Mitotic Spindle, part 1

submitted by: icamvid

Presented at the I2CAM/FAPERJ Spring School, 2008 in Rio de Janeiro, Brazil
Clements (0:00)
Speaker 2 (47:50)

Long Asters Rock The Spindle

submitted by: JCB
Astral microtubules help position the cytokinetic furrow by confining actomyosin contractility to the cell equator. Rankin and Wordeman reveal that if astral microtubules grow too long, they expand membrane blebs at the mitotic cell poles that squeeze the mitotic spindle back and forth between the two daughter cells. This biosights episode presents the paper by Rankin and Wordeman from the July 12, 2010 issue of The Journal of Cell Biology, and includes an interview with senior author Linda...

CyclinB1-Cdk1 Makes Its Move

submitted by: JCB
Cells drastically alter their structure at the onset of mitosis. Gavet and Pines reveal that the mitotic kinase CyclinB1-Cdk1 triggers its own nuclear import in prophase to ensure reorganization of the nucleus and cytoplasm is synchronized. This biosights episode presents the paper by Gavet and Pines from the April 19, 2010 issue of The Journal of Cell Biology, and includes an interview with senior author Jonathon Pines. Produced by Justin Paul and Ben Short. See the full article online...

Separating Duplicated Chromosomes in Preparation for Cell Division: Part 3: Moving the Chromosomes to the Spindle Poles: the Mechanisms of Anaphase A (41:27)

submitted by: scivee-team

The third lecture presents evidence, largely from McIntosh's lab, that shows how microtubule depolymerization can move chromosomes in vitro and explores the nature of some of the protein complexes that can couple chromosomes to microtubules and take advantage of this reaction.

Separating Duplicated Chromosomes in Preparation for Cell Division: Part 2: Understanding Mitosis through Experimentation (39:02)

submitted by: scivee-team

The second lecture describes some key experiments showing the dynamics of a formed mitotic spindle and the ways these may contribute to accurate chromosome motion. Experiments that reveal aspects of the processes by which chromosomes attach to the spindle are presented. Mitotic motors are introduced and discussed in the light of what they probably do and do not accomplish to effect chromosome motion, including acting to improve the accuracy of chromosome segregation.

Biology of Plants

submitted by: scivee-team

An overview of the process of photosynthesis and the biology of plants - function, reproduction and life.