Tip of the Week: MapMi, mapping miRNA sequences

submitted by: OpenHelix

Today's tip is on MapMi, a tool to map miRNA sequences to genomic sequences. See http://blog.openhelix.eu/?p=10282 for more information

Tip of the Week: RepTar, miRNA database

submitted by: OpenHelix

Today's tip of the week is on RepTar. To learn more about this tip, the database and other miRNA databases, visit the blog post on RepTar

Tip of the Week: CircuitsDB for TF/miRNA/gene Regulation Networks

submitted by: OpenHelix

For more information about this tip and resource see our blog post at http://blog.openhelix.eu/?p=5360. In this tip we introduce CircuitsDB, a database of MicroRNA / Transcription Factor Regulatory Circuits in Human and Mouse. We demonstrate a basic search and then explore the information provided in the result reports.

RNA Interference Proteins Tied to Cancer Survival Rates

submitted by: mdanderson
Levels of two proteins in a woman's ovarian cancer are strongly associated with her likelihood of survival, a research team led by scientists at The University of Texas M. D. Anderson Cancer Center reports in the Dec. 18 issue of the New England Journal of Medicine. The study shows that women with high levels of Dicer and Drosha, two proteins that are vital to a cell's gene-silencing machinery, had a median survival of 11 years. For those with low levels of both proteins, median survival...