Rape with Extreme Violence: the new pathology in eastern DR Congo

submitted by: nangini
Rape with extreme violence characterizes the deliberate and mutilating assaults on women in girls by militia in eastern DR Congo. Through the lens of the Panzi Hospital in South Kivu, we discuss the medical and socioeconomic impact of REV, and highlight some of its underlying factors. Dr. Mukwege, short-listed for the Nobel Peace prize for the second time this year, offers powerful first-hand experience as as founder and director of the Panzi Hospital. "We don't lose hope...I know that with...

Statistical Analysis and Data Mining

submitted by: TimHowles
Presented by John Elder, Elder Research, Inc. and the University of Virginia, Charlottesville, USA. John Elder and Elsevier Publishers are delighted to present this short video, extracted from training material produced by Elder Research, Inc. In this video, John introduces some of the mistakes to avoid during the data mining process. This video will be of interest to business intelligence organisations and financial analysts, but also to anyone needing to extract information from large...

Apicomplexan Parasites, Pathogen Genome Informatics, and the Evolution of Eukaryotic Organelles: Part 3C: Designing and mining pathogen genome databases: From genes to drugs and vaccines (25:45)

submitted by: video_collector
With the emergence of genomic-scale datasets representing all of the genes in the genome, all of the proteins in a cell or tissue, and all of the interactions and signals in an organism, biologists are increasingly faced with the challenge of how to store, integrate, and interrogate this information. How can we effectively mine large-scale datasets to expedite biological discovery, for example in the identification of new targets for anti-parasitic drug and vaccine design? Computational...

Apicomplexan Parasites, Pathogen Genome Informatics, and the Evolution of Eukaryotic Organelles: Part 3B: Designing and mining pathogen genome databases: From genes to drugs and vaccines (27:10)

submitted by: video_collector
With the emergence of genomic-scale datasets representing all of the genes in the genome, all of the proteins in a cell or tissue, and all of the interactions and signals in an organism, biologists are increasingly faced with the challenge of how to store, integrate, and interrogate this information. How can we effectively mine large-scale datasets to expedite biological discovery, for example in the identification of new targets for anti-parasitic drug and vaccine design? Computational...

Apicomplexan Parasites, Pathogen Genome Informatics, and the Evolution of Eukaryotic Organelles: Part 3A: Designing and mining pathogen genome databases: From genes to drugs and vaccines (20:04)

submitted by: video_collector
With the emergence of genomic-scale datasets representing all of the genes in the genome, all of the proteins in a cell or tissue, and all of the interactions and signals in an organism, biologists are increasingly faced with the challenge of how to store, integrate, and interrogate this information. How can we effectively mine large-scale datasets to expedite biological discovery, for example in the identification of new targets for anti-parasitic drug and vaccine design? Computational...

Cytoskeletal Motor Proteins: Part 3: Mining the Genome for Mitotic Treasures (33:41)

submitted by: scivee-team
The third (last) part of the lecture is on mitosis, the process by which chromosomes are aligned and then segregated during cell division. I will describe our efforts to find new proteins that are important for mitosis through a high throughput RNAi screen. I will discuss how we technically executed the screen and then focus on new proteins that are we discovered that are involved in generating the microtubules that compose the mitotic spindle. I also discuss the medical importance of...