Dynein and kinesin generate nuclear power

submitted by: JCB
Many cellular processes, including polarization and differentiation, require the nucleus to move to a specific location within the cytoplasm. Fridolfsson and Starr reveal how the microtubule motors dynein and kinesin-1 control the bi-directional movements of nuclei in the embryonic hypoderm of C. elegans. This biosights episode presents the paper by Fridolfsson and Starr from the October 4, 2010 issue of The Journal of Cell Biology, and includes an interview with senior author Daniel Starr...