Incidence of MGUS and Estimation of Duration Before Recognition

submitted by: WentzMR
Dr. Terry Therneau, a Professor of Biostatistics at Mayo Clinic in Rochester, MN, discusses his article appearing online first and in the November 2012 issue of Mayo Clinic Proceedings, placing the surprising outcome among the statistics discovered in the study into perspective. Available at: http://www.mayoclinicproceedings.org/article/ S0025-6196(12)00634-9/fulltext

Incidence of MGUS & Estimation of Duration Before First Clinical Recognition

submitted by: WentzMR

Dr. Robert Kyle, professor of medicine, laboratory medicine and pathology, at Mayo Clinic in Rochester, MN, discusses his article appearing online first and in the November 2012 issue of Mayo Clinic Proceedings, where he defines MGUS and explains its role in the development of multiple myeloma and other blood disorders.
Available at: http://www.mayoclinicproceedings.org/article/S0025-6196(12)00634-9/fulltext

Use of Nonclonal Serum Immunoglobulin Free Light Chains to Predict Overall Survival in the General Population.

submitted by: WentzMR

Dr. S. Vincent Rajkumar, Professor of Medicine in the Division of Hematology at Mayo Clinic in Rochester, MN, illuminates the results an article appearing in the June 2012 issue of Mayo Clinic Proceedings of an Olmsted County population- based study where detection of high polyclonal free light chain levels can predict mortality outcomes across multiple conditions. Available at:
http://www.mayoclinicproceedings.org/article/S0025-6196(12)00388-6 /fulltext

Advances in the Diagnosis, Classification, Risk Stratification, and Management of Monoclonal Gammopathy of Undetermined Signific

submitted by: mcgheekkm

Dr. S. Vincent Rajkumar, from the Division of Hematology at Mayo Clinic, discusses advances in the diagnosis, classification, risk stratification, and management of monoclonal gammopathy of undetermined significance and implications for recategorizing disease entities, which will be published in the October 2010 issue of Mayo Clinic Proceedings (Available at: http://tinyurl.com/39g8n6x).

Dr Shaji K Kumar of Mayo Clinic discusses Dec 2009 Mayo Clinic Proceedings article on updated mSMART Consensus Guidelines

submitted by: mcgheekkm
Dr. Shaji K Kumar, Associate Professor of Hematology and Medicine at Mayo Clinic in Rochester, MN, discusses updated Mayo Stratification of Myeloma and Risk-Adapted Therapy (mSMART) Consensus Guidelines (direct link available at http://tiny.cc/V2dk9 or visit journal at www.mayoclinicproceedings.com ). The identification of well-defined and reproducible prognostic factors and introduction of new therapies with unique modes of action and impact on disease outcome have for the first time...

Disease Associations With MGUS--Mayo Clinic study published in Mayo Clinic Proceedings

submitted by: mcgheekkm

Dr. S. Vincent Rajkumar, Mayo Clinic hematologist, discusses the first systematic study (published in August issue of Mayo Clinic Proceedings available at http://tinyurl.com/lr55lc) to determine association of Monoclonal Gammopathy of Undetermined Significance (MGUS) with all diseases in 17,398 patients.