Around the Nucleus

submitted by: ahernk

This video is a surreal presentation of a Metabolic Melody by Kevin Ahern (www.davincipress.com/metabmelodies.html for more info). The tune is The Beatle's "Across the Universe." The lyrics and video are by Kevin Ahern and the recording is by David Simmons

Deriving rules and assertions from pharmacogenomics knowledge resources in support of patient drug metabolism efficacy...

submitted by: Jamia
Full title: Deriving rules and assertions from pharmacogenomics knowledge resources in support of patient drug metabolism efficacy predictions Abstract: Objective Pharmacogenomics evaluations of variability in drug metabolic processes may be useful for making individual drug response predictions. We present an approach to deriving ‘phenotype scores’ based on existing pharmacogenomics knowledge and a patient's genomics data. Pharmacogenomics plays an important role in the bioactivation...

Metabonomic profiling of the gut microbiome: Implications for human health James Kinross, Imperial College, London

submitted by: dougramsey
Microbial-mammalian metabolic cooperation is defined as the human ‘metabonome’. Transgenomic co-metabolic interactions within the metabonome greatly increase system complexity and this presents a significant challenge for elucidating the mechanisms by which the intestinal micro biome influences the host phenotype. By measuring and mathematically modelling changes in the levels of products of metabolism found in mammalian biological fluids and tissues, metabonomics offers fresh insight...

Advances to the Biochemical, Genetic and Genomic (BiGG) Database

submitted by: jypark
The BiGG database is a widely used resource for sharing genome-scale metabolic reconstructions. BiGG integrates several published genome-scale metabolic networks into one resource with standard nomenclature which allows components to be compared across different species. Furthermore, BiGG contains links to several publicly available databases where additional information can be found and integrated. In addition, BiGG contains a customized export tool that enables the generation of SBML...

It’s easy to get lost on the biological superhighway. Thankfully, we brought a map.

submitted by: dabraham
Biological annotations and terms have gotten a makeover with RGD’s interactive pathway diagrams. The Rat Genome Database makes biological pathways and their components easy to navigate and analyze through this newly added diagrams feature at http://rgd.mcw.edu/wg/pathway?100 . This video will show you how to easily access, view, and gather information from these diagrams and all the great tools they offer. See our RGD website at http://rgd.mcw.edu for more information and tools for...