The Dictyostelium type V myosin MyoJ is responsible for the cortical association and motility of contractile vacuole membranes

submitted by: JCB
The contractile vacuole (CV) complex in Dictyostelium is a tubulovesicular osmoregulatory organelle that exhibits extensive motility along the actin-rich cortex, providing a useful model for investigating myosin-dependent membrane transport. Here, we show that the type V myosin myoJ localizes to CV membranes and is required for efficient osmoregulation, the normal accumulation of CV membranes in the cortex, and the conversion of collapsed bladder membranes into outwardly radiating cortical...
Authors: G Jung, Ma Titus, Ja Hammer