20130620 - Protein Prediction 1 - Burkhard Rost - Membrane helix prediction

submitted by: rostlab

Date: 20130620

Course: Protein Prediction 1

Title: Membrane helix prediction

Speaker: Burkhard Rost

Audience: Computational Biology students

20130620 - Protein Prediction 1 - Burkhard Rost - Membrane helix prediction

submitted by: rostlab

Date: 20130620

Course: Protein Prediction 1

Title: Membrane helix prediction

Speaker: Burkhard Rost

Audience: Computer Science students

T cell signaling goes with the flow

submitted by: JCB
Activated T cell receptors stimulate actin polymerization at the periphery of the immunological synapses that form between lymphocytes and antigen-presenting cells. Babich et al. reveal that the retrograde flow of actin, largely driven by continuous polymerization, is required to sustain downstream signaling events and T cell activation. This biosights episode presents the paper by Babich et al. from the June 11, 2012 issue of The Journal of Cell Biology and includes an interview with senior...

Revolutionary Advancement in Membrane Filtration Sample Preparation for Biotech Industry

submitted by: putnamr2
Photonic BioSystems, Inc. unveils game-changing microbiological testing technology. The versatile, enclosed filtration cartridge-based sample preparation technique is expected to change the paradigm of membrane filtration sample testing. Video Contents: 0:00 Filter system design explained 1:50 How the filtration system works: exemplary sample processing 4:40 Small volume samples 5:55 The filter system does what In-line filter cartridges cannot do 7:20 Variations on the...

New Methods for Computer- Aided Drug Design and Atomically Detailed Models of Protein Regulation

submitted by: icamvid

Matt Jacobson discusses new methods for computer- aided drug design and atomically detailed models of protein regulation. He includes flexible binding sites, homology modeling, membrane permeability, physics- based scoring, phosphorylation, and pH defense.

Nuclear envelope starts with a clean sheet

submitted by: JCB
At the start of mitosis, the nuclear envelope and nuclear pore complexes break down and disperse into the endoplasmic reticulum and cytoplasm. Lu et al. use rapid, 3D live cell imaging to reveal that, in contrast to previous models, the nuclear envelope reforms directly from ER cisternae after mitosis and that this happens before nuclear pore complexes start to reassemble. This biosights episode presents the paper by Lu et al. from the August 8, 2011, issue of The Journal of Cell Biology,...

Synaptic Land - The Movie

submitted by: KidsJudgePartnership
The story of how two behavioral neuroscience graduate students from Oregon Health & Science University conceived and constructed the very first "Synaptic Land", a game that helps kids learn about processes involved in neurotransmission. Since its debut at the Oregon Kids Judge! Neuroscience Fair held at OMSI in 2002, undergraduate and graduate students at many other universities have created their own versions of the Synaptic Land game (e.g., PENN, University of Scranton, California...

Emergent Structures in Models of Biological Membranes

submitted by: icamvid

Tonya Kuhl presents research on biological structure formation such as lipid bilayers.

Deep-Ocean Metagenomics: Comparative Investigations of Microbes Inhabiting Hydrothermal Vents and the Cold Deep Ocean

submitted by: dougramsey
The deep-ocean accounts for the majority of the water on our planet. While the cold deep-ocean is the dominant nutrient-challenged ecosystem, hydrothermal vents represent oases along tectonically active areas of the seafloor. Hydrothermal vents and the surrounding cold deep-ocean each support unique communities of microbes and viruses that have become highly adapted to local conditions. Through cycles of infection and host cell lysis, bacteriophages (viruses that specifically infect...

Protein Secretion and Vesicle Traffic by Randy Schekman - Part 1: Genetic Dissection of the Secretory Pathway (36:35)

submitted by: video_collector
Protein secretion is executed by a cellular pathway involving the delivery of membrane and soluble secretory proteins in vesicles that capture newly-synthesized proteins assembled in the endoplasmic reticulum (ER) and sorted in the Golgi apparatus. Vesicles fuse with the plasma membrane resulting in the discharge of soluble molecules to the cell exterior and integration of vesicle membrane proteins and lipids in the cell surface. Baker's yeast cells grow by vesicle fusion and secretion at...