The Limits of Acceptable Biological Variation in Elite Athletes: Should Sex Ambiguity Be Treated Differently from Other Advantag

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Dr. J. Michael Bostwick, Professor of Psychiatry at Mayo Clinic in Rochester, MN, discusses his article appearing in the June 2012 issue of Mayo Clinic Proceedings, where he explores sex, gender, and other genetic traits in elite athletes. Available at: http://www.mayoclinicproceedings.org/article/S0025-6196(12)00439-9/fulltext

Use of Nonclonal Serum Immunoglobulin Free Light Chains to Predict Overall Survival in the General Population.

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Dr. S. Vincent Rajkumar, Professor of Medicine in the Division of Hematology at Mayo Clinic in Rochester, MN, illuminates the results an article appearing in the June 2012 issue of Mayo Clinic Proceedings of an Olmsted County population- based study where detection of high polyclonal free light chain levels can predict mortality outcomes across multiple conditions. Available at:
http://www.mayoclinicproceedings.org/article/S0025-6196(12)00388-6 /fulltext

The Obesity Paradox, Cardiorespiratory Fitness, and Coronary Heart Disease

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Dr. Carl (Chip) Lavie, a cardiologist from Ochsner Clinic in New Orleans, LA, discusses an article appearing in the May 2012 issue of Mayo Clinic Proceedings, which provides further evidence for the validation of the obesity paradox. Previous study results may be misleading if fitnessof the patient is not also considered.
Available at: http://www.mayoclinicproceedings.org/article/S0025-6196(12)00266-2/fulltext

Dr. Thomas Gerber discusses the articles featured on the cover page of the May 2012

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Dr. Thomas Gerber, Associate Editor for Mayo Clinic Proceedings, discusses the articles featured on the cover page of the May 2012 issue. These include: •Relationship of Zolpidem and Cancer Risk: A Taiwanese Population-Based Cohort Study, by Dr. Chia Hung Kao and colleagues; and its accompanying editorial, Insomnia, Hypnotic Drug Use, and Patient Well-being: First, Do No Harm, by Dr. Barbara Phillips •Anthropometric Correlates of Total Body Fat, Abdominal Adiposity, and...

Computer Activities, Physical Exercise, Aging, and Mild Cognitive Impairment:

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Dr. Yonas Geda, a physician scientist at Mayo Clinic in Scottsdale, Arizona, USA, discusses his article appearing in the May 2012 issue of Mayo Clinic Proceedings. The study shows a synergistic interaction between computer use and moderate physical exercise in being associated with a decreased odds of having mild cognitive impairment, the intermediate stage between normal aging and dementia. Available at: http://www.mayoclinicproceedings.org/article/S0025-6196(12)00304-7/fulltext

Common Musculoskeletal Tumors of Childhood and Adolescence

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Dr. Carola Arndt, a pediatric hematologist from Mayo Clinic in Rochester, MN, discusses her article appearing in the May 2012 issue of Mayo Clinic Proceedings, and reviews the diagnosis, prognosis, staging, multidisciplinary therapy, new directions in therapy,
and long-term complications of treatment for common childhood tumors. Available at:
http://www.mayoclinicproceedings.org/article/S0025-6196(12)00301-1/fulltext

Ten Recommendations for Closing the Credibility Gap in Reporting

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Dr. Daniel Haller and Bernadette Mansi describe results of an article appearing in the May 2012 issue of Mayo Clinic Proceedings detailing a collaboration between industry representatives and medical journal editors to characterize the credibility gap in reporting industry-sponsored research and identify potential approaches to resolve it. Available at:
http://www.mayoclinicproceedings.org/article/S0025-6196(12)00298-4/fulltext

Meta-analysis of Vancomycin for the Treatment of Patients

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Dr. Konstantinos Vardakas, Internal Medicine physician from Alfa Institute of Biomedical Sciences, in Athens, Greece, reviews his article appearing in the April 2012 issue of Mayo Clinic Proceedings, which compares the effectiveness of vancomycin and other antibiotics in treating patients with gram-positive infections. Available at:
http://www.mayoclinicproceedings.org/article/S0025-6196(12)00208-X/fulltext

: Increasing Incidence of Melanoma Among Young Adults: An Epidemiologic Study in Olmsted County, Minnesota.

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: Dr. Kurtis Reed, a Resident Physician in the Department of Dermatology at Mayo Clinic in Rochester, MN, discusses his article appearing in the April 2012 issue of Mayo Clinic Proceedings on a retrospective chart study using data from the Rochester Epidemiology Project that reveals a significant increase in the incidence of melanoma in young adults. Available at:
http://www.mayoclinicproceedings.org/article/S0025-6196(12)00209-1/fulltext

Total Knee Arthroplasty Outcomes in Top-ranked and Non-top-ranked Orthopaedic Hospitals: An Analysis of Medicare Administrative

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Dr. Peter Cram, Associate Professor of Medicine at the University of Iowa, Carver College of Medicine, in Iowa City, IA, discusses his article appearing in the April 2012 issue of Mayo Clinic Proceedings, which compares outcomes for Medicare patients undergoing primary total knee arthroplasty in US News and World Report top-ranked orthopedic hospitals and competing non–top-ranked hospitals. The study found that top-ranked hospitals did not have lower complication rates, readmission rates,...