Clinical Spectrum, Frequency and Significance of Myocardial Dysfunction in Severe Sepsis and Septic Shock

submitted by: WentzMR
Dr. Juan N. Pulido, Assistant Professor of Anesthesiology and Consultant in Critical Care Medicine and Adult Cardiovascular Anesthesia at Mayo Clinic in Rochester, MN, interprets the results of a study described in the July 2012 issue of Mayo Clinic Proceedings on the Clinical spectrum, frequency and significance of myocardial dysfunction in patients with severe sepsis and septic shock using transthoracic echocardiography. Available at:...

The Elders Risk Assessment (ERA) Index, an Electronic Administrative Database Derived Frailty Index, Can Identify Risk for Hip F

submitted by: WentzMR

Dr. Mohammad Albaba, Geriatric Hospitalist at Mayo Clinic in Rochester, MN, discusses his article appearing in the July 2012 issue of Mayo Clinic Proceedings that evaluates a computer-based administrative frailty index which can assess risk for hip fracture in community dwelling older adults. The index allows for a more cost effective way to identify individuals at risk. Available at: http://www.mayoclinicproceedings.org/article/S0025-6196(12)00482-X/fulltext

Gastric Acid Suppression and Outcomes in Clostridium difficile Infection: A Population-Based Study.

submitted by: WentzMR

Dr. Sahil Khanna, Gastroenterology Fellow at Mayo Clinic in Rochester, MN, discusses his article appearing in the July 2012 issue of Mayo Clinic Proceedings on the effects of medications, including proton pump inhibitors (PPI) and histamine type 2 (H2) blockers, on outcomes in patients with Clostridium difficile infection (CDI) in a population-based cohort. Available at: http://www.mayoclinicproceedings.org/article/S0025-6196(12)00483-1/fulltext

Potential Adverse Cardiovascular Effects from Excessive Endurance Exercise

submitted by: WentzMR

Dr. James O’Keefe, Clinical Cardiologist from Saint Luke’s Mid America Heart Institute in Kansas City, Missouri, describes the risks and benefits of extreme endurance exercise, emphasizing the importance of moderation. Available at:
http://www.mayoclinicproceedings.org/article/S0025-6196(12)00473-9/fulltext

Effectiveness of Patient-Collected Swabs for Influenza Testing

submitted by: WentzMR

Dr. Bobbi Pritt, Laboratory Director of Clinical Virology and Parasitology at Mayo Clinic in Rochester, MN, shares results of a study appearing in the June 2012 issue of Mayo Clinic Proceedings which measures the accuracy and patient satisfaction of a self-swabbing technique for detection of influenza.
Available at: http://www.mayoclinicproceedings.org/article/S0025-6196(12)00300-X/fulltext

Evaluating the Patient with Diarrhea: A Case-Based Approach

submitted by: WentzMR

Dr. Seth Sweetser, Assistant Professor of Medicine in the Division of Gastroenterology and Hepatology at Mayo Clinic in Rochester, MN, discusses his article appearing in the June 2012 issue of Mayo Clinic Proceedings where he shares a 5 step approach for assessing diarrhea in patients and shares 3 cases demonstrating the practical applications of the evaluation. Available at:
http://www.mayoclinicproceedings.org/article/S0025-6196(12)00382-5/fulltext

Statins in heart failure: The paradox between large randomized clinical trials and real life.

submitted by: WentzMR
Dr. Paloma Gastelurrutia, a researcher at Germans Trias i Pujol Health Research Institute, in Barcelona, Spain, discusses her article appearing in the June 2012 issue of Mayo Clinic Proceedings, which compares the results of clinical trial studies and long term follow-up with real-life cohorts of patients using statins. Large clinical trials did not show success with statins, but cohort studies revealed more optimistic results. Available at:...

The Limits of Acceptable Biological Variation in Elite Athletes: Should Sex Ambiguity Be Treated Differently from Other Advantag

submitted by: WentzMR

Dr. J. Michael Bostwick, Professor of Psychiatry at Mayo Clinic in Rochester, MN, discusses his article appearing in the June 2012 issue of Mayo Clinic Proceedings, where he explores sex, gender, and other genetic traits in elite athletes. Available at: http://www.mayoclinicproceedings.org/article/S0025-6196(12)00439-9/fulltext

Use of Nonclonal Serum Immunoglobulin Free Light Chains to Predict Overall Survival in the General Population.

submitted by: WentzMR

Dr. S. Vincent Rajkumar, Professor of Medicine in the Division of Hematology at Mayo Clinic in Rochester, MN, illuminates the results an article appearing in the June 2012 issue of Mayo Clinic Proceedings of an Olmsted County population- based study where detection of high polyclonal free light chain levels can predict mortality outcomes across multiple conditions. Available at:
http://www.mayoclinicproceedings.org/article/S0025-6196(12)00388-6 /fulltext

The Obesity Paradox, Cardiorespiratory Fitness, and Coronary Heart Disease

submitted by: WentzMR

Dr. Carl (Chip) Lavie, a cardiologist from Ochsner Clinic in New Orleans, LA, discusses an article appearing in the May 2012 issue of Mayo Clinic Proceedings, which provides further evidence for the validation of the obesity paradox. Previous study results may be misleading if fitnessof the patient is not also considered.
Available at: http://www.mayoclinicproceedings.org/article/S0025-6196(12)00266-2/fulltext