Multi-Cellular Rosettes in the Mouse Visceral Endoderm Facilitate the Ordered Migration of Anterior Visceral Endoderm Cells

submitted by: AaronSmith
Find the article at http://www.plosbiology.org/article/info:doi/10.1371/journal.pbio.1001256 . The visceral endoderm (VE) is a simple epithelium that forms the outer layer of the egg-cylinder stage mouse embryo. The anterior visceral endoderm (AVE), a specialised subset of VE cells, is responsible for specifying anterior pattern. AVE cells show a stereotypic migratory behaviour within the VE, which is responsible for correctly orientating the anterior-posterior axis. The epithelial...

Male Circumcision for HIV Prevention in High HIV Prevalence Settings

submitted by: ahyde
Male Circumcision for HIV Prevention in High HIV Prevalence Settings: What Can Mathematical Modelling Contribute to Informed Decision Making? Video by Catherine Hankins of UNAIDS. This relates to an article published in PLoS Medicine in September 2009 in which experts from UNAIDS, WHO, and the South African Centre for Epidemiological Modelling report their review of mathematical models estimating the impact of male circumcision on HIV incidence in high HIV prevalence settings *...