Addressing Peptide ID Signal-to-Noise with Target-Decoy Searching (Proteomics)

submitted by: dachian

How to improve signal-to-noise in proteomics search engine results from tandem mass spectrometry

Modeling Fragmentation Patterns of ECD/ETD Mass Spectrometers

submitted by: patel.anandd

Mass spectrometers are sophisticated instruments that detect the mass of ionized molecules, which is useful in the field of chemistry and most recently proteomics. Newer spectrometers ionize and fragment molecules with different specificity and resolution, which requires understanding and applying these newer fragmentation patterns to current peptide sequencing algorithms like InsPect.