The Importance of Technology in the 'Omics Lab

submitted by: Chrom Solutions

Dr. Matthias Mann, Director of the Max Planck Institute of Biochemistry, talks about how impactful innovative technology, like the Orbitrap, has been in his lab. The end goal of his collaboration with Thermo Fisher Scientific is to build a system that anyone can use to "dramatically extend the reach and impact of proteomics.

Large-scale Phosphorylation Analysis (Proteomics): Dr. Sean Beausoleil, Harvard

submitted by: dachian

Analyzing phosphopeptides using proteomics mass spectrometry is challenging, especially for large-scale data sets. The problem and solution is discussed by Dr. Sean Beausoleil (Harvard Medical School), who is the co-inventor of the ASCORE algorithm for phosphorylation site localization.

Addressing Peptide ID Signal-to-Noise with Target-Decoy Searching (Proteomics)

submitted by: dachian

How to improve signal-to-noise in proteomics search engine results from tandem mass spectrometry

Peptide ID and protein inference using PeptideProphet and ProteinProphet

submitted by: dachian

Advanced proteomics data analysis for identifying peptides and proteins with high sensitivity and specificity using proteomics mass-spectrometry.

Fast & reliable transition design using MRMaid: new analysis & results

submitted by: bixgurl

MRMaid [1] (pronounced ‘mermaid’) aims to answer the most challenging question faced by researchers attempting to perform MRM (multiple reaction monitoring).

Translational Proteomics 2.0 Meeting: SEQUEST and TPP Tips

submitted by: dachian

Advanced tips on using SEQUEST and TPP by Jimmy Eng of U. of Washington, the co-inventor of SEQUEST