There are more than 5000 species of single-celled eukaryotes in the biological phylum known as the Apicomplexa, including the parasites responsible for malaria, neurological birth defects, and opportunistic infections associated with HIV/AIDS. These ancient protozoa provide a unique window into the evolution of subcellular organelles that have long fascinated cell biologists. Familiar features help to elucidate the origins, functions and design parameters for the secretory pathway,...

Jean-Claude Bradley guest lectures on Rajarshi Guha's cheminformatics course at Indiana University. After an introduction to Open Notebook Science and the synthesis of anti-malarial compounds, topics include SMILES, InChIs, InChIKeys, CMLRSS, JCAMP-DX, JSpecView, ExcelVBA, blogs, wikis and Second Life.

A brief overview of research in Jean-Claude Bradley's laboratory at Drexel University, including the synthesis of anti-malarial compounds and some screenshots of the Open Notebook Science project UsefulChem.