Richard Lenski: Evolution in a Flask (MWV61)

submitted by: MicrobeWorld
In episode 61 of MicrobeWorld Video, filmed at the American Association for the Advancement of Science Meeting in Vancouver, Canada on February 17th, 2012, Dr. Stan Maloy talks with Richard Lenski Ph.D., Hannah Professor of Microbial Ecology, Michigan State University, about his research into the evolution of bacteria and the new frontier of digital evolution. Lenski's Long Term Evolution Experiment with E. coli has seen over 50,000 new generations since its inception in 1998. This has led...

Electrostatics and long-range coupling in Src kinase activation

submitted by: icamvid

Carol Post gives a talk at the RPP08 conference on Src, a mechanism of conformational activation. She covers two topics regarding it Src:
1) Switched electrostatic network
2) long-range coupling of regulatory SH2/SH3 and catalytic domain

An Accelerated View of Functional Dynamics in Bio-Molecular Systems

submitted by: icamvid

Phineus Markwick gives a talk at the RPP08 conference long time-scale MD simulations of protein dynamics. He discusses experiments using dipolar coupling to probe the protein dynamics. From these he shows how to build a simulation.