Weight-loss diets in people with type 2 diabetes and renal disease: a randomized controlled trial of the effect of different dietary protein amounts

submitted by: Peter Clifton
ABSTRACT Background: Higher-protein weight-loss diets (defined as >25% of energy as protein) are not recommended for individuals with type 2 diabetes because of their potential adverse effect on renal function. Objective: We aimed to examine the effect of such diets on renal function over 12 mo in people with type 2 diabetes and early renal disease. Design: Overweight and obese people with type 2 diabetes were screened to identify those with an albumin:creatinine ratio from 3 to...
Authors: David Jesudason, Eva Pedersen, Peter Clifton

Greater whole-grain intake is associated with lower risk of type 2 diabetes, cardiovascular disease, and weight gain

submitted by: sarachacko
Whole-grain and high fiber intakes are routinely recommended for prevention of vascular diseases; however, there are no comprehensive and quantitative assessments of available data in humans. The aim of this study was to systematically examine longitudinal studies investigating whole-grain and fiber intake in relation to risk of type 2 diabetes (T2D), cardiovascular disease (CVD), weight gain, and metabolic risk factors. We identified 45 prospective cohort studies and 21...
Authors: Sara A. Chacko, Eva Qing Ye, Elizabeth L. Chou, Matthew Kugizaki, Simin Liu

Effects of n-6 PUFAs compared with SFAs on liver fat, lipoproteins, and inflammation in abdominal obesity: a randomized controlled trial

submitted by: Iggman
ABSTRACT Background: Replacing SFAs with vegetable PUFAs has cardiometabolic benefits, but the effects on liver fat are unknown. Increased dietary n-6 PUFAs have, however, also been proposed to promote inflammation—a yet unproven theory. Objective: We investigated the effects of PUFAs on liver fat, systemic inflammation, and metabolic disorders. Design: We randomly assigned 67 abdominally obese subjects (15% had type 2 diabetes) to a 10-wk isocaloric diet high in vegetable n-6...
Authors: Helena Bjermo

The impact of low- and high-density lipoproteins on inwardly-rectifying K+ channels in macrophages

submitted by: devkaram

Dev Singh shares his poster presentation at the Experimental Biology 2008 conference.