Immunotherapy: unleashing immune system to attack cancer

submitted by: mdanderson
Cancer immunotherapy treats the immune system rather than the tumor. Jim Allison, Ph.D., professor in Immunology at MD Anderson Cancer Center, has developed an innovative approach that will open doors for treating all types of cancer. Padmanee Sharma, M.D., Ph.D., associate professor in Genitourinary Medical Oncology and Immunology, is lead scientist on immunotherapy clinical trials. Listen to Allison and Sharma discuss their collaboration on MD Anderson’s Moon Shots Program to develop...

Antibiotic resistant hospital bacteria

submitted by: COMED2010
MOSAR aims to significantly advance our knowledge regarding the control of antimicrobial resistance of bacteria responsible for major and emerging nosocomial diseases in hospitals, which are now spreading into communities. MOSAR will examine the factors determining the dynamics of spread of AMRB within healthcare facilities and the relative efficacity and medicoeconomic impact of control strategies. The resulting new knowledge will be disseminated to caregivers and health policy makers and...

Path to Tumor Destruction

submitted by: mdanderson

Th17 sets off a chain of events that ends with custom-made killer T cells destroying tumors.

Helper T Cell Guides Killer Cells to Cancer

submitted by: mdanderson

Cancer manages to suppress or elude the body's immune system to survive and grow. Scientists at The University of Texas M. D. Anderson Cancer Center show this week in the journal Immunity how the helper T cell Th17 awakens the immune system to attack cancer. Senior author Chen Dong discusses the findings and their potential application for patients.

TGFß & Alzheimer's Disease

submitted by: alex01

R.A. Flavell (Yale University, New Haven, CT) discusses the role of Transforming Growth Factor ß (TGFß) in disease. In the central nervous system of a murine model of AD this cytokine appears to prevent macrophages from attacking ß-amyloid. Flavell visualizes that selective blockade of this TGFß
activity could lead to the destruction of plaques in patients with AD.

Therapies for Multiple Sclerosis

submitted by: alex01

J. Kocsis, PhD. - The current approaches to the therapy of multiple sclerosis are reviewed by J. Kocsis (Yale University). His research emphasizes remyelination as an approach to the therapy of multiple sclerosis and spinal cord injury.