NetMHCpan, a Method for Quantitative Predictions of Peptide Binding to Any HLA-A and -B Locus Protein of Known

submitted by: mniel
Background Binding of peptides to Major Histocompatibility Complex (MHC) molecules is the single most selective step in the recognition of pathogens by the cellular immune system. The human MHC class I system (HLA-I) is extremely polymorphic. The number of registered HLA-I molecules has now surpassed 1500. Characterizing the specificity of each separately would be a major undertaking. Principal Findings Here, we have drawn on a large database of known...
Authors: Morten Nielsen, Claus Lundegaard, Thomas Blicher, Kasper Lamberth, Mikkel Harndahl, Sune Justesen, Gustav Røder, Bjoern Peters, Alessandro Sette, Ole Lund, Søren Buus