Correcting for Inflammation Changes Estimates of Iron Deficiency among Rural Kenyan Preschool Children

submitted by: ebogrant5
The assessment of iron status where infections are common is complicated by the effects of inflammation on iron indicators and in this study we compared approaches that adjust for this influence. Blood was collected in 680 children (aged 6–35 mo) and indicators of iron status [(hemoglobin (Hb), zinc protoporphyrin (ZP), ferritin, transferrin receptor (TfR), and TfR/ferritin index)] and subclinical inflammation [(the acute phase proteins (APP) C-reactive protein (CRP), and a-1-acid...
Authors: Frederick Grant, Parminder Suchdev, Rafael Flores-Ayala, Conrad Cole, Usha Ramakrishnan, Laird Ruth, Reynaldo Martorell

Pharmacogenomic Biomarkers for Prediction of Severe Adverse Drug Reactions

submitted by: KuoOffice

Dr. Magnus Ingelman-Sundberg presents his recent paper on "Pharmacogenomic biomarkers for prediction of "severe adverse drug reactions" published in the New England Journal of Medicine on Feb 2008.

The Effect of Universal Influenza Immunization on Mortality and Health Care Use

submitted by: jeff_kwong
Background In 2000, Ontario, Canada, initiated a universal influenza immunization program (UIIP) to provide free influenza vaccines for the entire population aged 6 mo or older. Influenza immunization increased more rapidly in younger age groups in Ontario compared to other Canadian provinces, which all maintained targeted immunization programs. We evaluated the effect of Ontario's UIIP on influenza-associated mortality, hospitalizations, emergency department (ED) use, and visits to...
Authors: Jeffrey c. Kwong, Thérèse a. Stukel, Jenny Lim, Allison j. Mcgeer, Ross e.g. Upshur, Helen Johansen, Christie Sambell, William w. Thompson, Deva Thiruchelvam, Fawziah Marra, Lawrence w. Svenson, Douglas g. Manuel