Folding pathway of the B1 domain of protein G explored by a multiscale modeling

submitted by: sekmi
The understanding of the folding mechanisms of single domain proteins is an essential step in the understanding of protein folding in general. Recently, we developed a mesoscopic CABS protein model which was successfully applied in protein structure prediction, studies of protein thermodynamics and modeling of protein complexes. In the present research this model is employed in a detailed characterization of the folding process of a simple globular protein, the B1 domain of IgG-binding...
Authors: Sebastian kmiecik and andrzej Kolinski