Background: Folate, choline, and betaine participate in homocysteine
metabolism. It is not known whether they interact during pregnancy.
Objective: The objective was to investigate how folate status affects
choline, betaine, and dimethylglycine during pregnancy.
Design: Fasting plasma folate, cobalamin, free choline, betaine, dimethylglycine,
and total homocysteine (tHcy) were measured longitudinally
at ,12, 15, 24–27, and 34 gestational weeks (GW); at labor
Authors: Silvia Fernandez-Roig, Michelle M Murphy