Obesity and Metabolic Syndrome

submitted by: alex01

F. X. Pi-Sunyer, MD defines metabolic syndrome and obesity and discusses the design and preliminary results of the Look AHEAD trial involving the importance of life style modification in the prevention of cardiovascular complications in patients with type II diabetes. Current and potential approaches to the therapy of obesity include modulators of the endocannabinoid system, drugs affecting free fatty acid synthesis and metabolism as drugs capable of increasing metabolic expenditure.